The St. John's Training School for Boys opened in 1956 and was operated by the (Catholic) lay order of the Brothers of the Christian Schools, which also operated a similar facility in Alfred (known as 'St. Joseph's, just outside of Ottawa).

Funded in large part by the province of Ontario, this facility housed orphans, truants, Children’s Aid Society referrals, juvenile delinquents, physically and perceptually challenged children, "incorrigibles" from reservation schools, and children of broken or poor homes which could not adequately support them. Both the Alfred and Uxbridge facilities were supervised by the Province.

More than 1,200 former residents of St. John's and St. Joseph's, suffered neglect and in some cases physical and sexual abuse at the hands of the Christian Brothers from the 1940s to the 1970s. A sweeping OPP investigation resulted in more than 200 charges against more than 30 people. The Catholic Church and the Christian Brothers later signed a $23-million reconciliation agreement and in 2004 the Ontario government formally apologized to the sexually and physically abused former residents. Charges ranged from "assault causing bodily harm" to "indecent assault" and "sodomy".